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Article

Effect of alcohol and its metabolites in lung cancer: CAPUA study.

Medicina clinica - 21 Jun 2017

Álvarez-Avellón Sara M, Fernández-Somoano Ana, Navarrete-Muñoz Eva M, Vioque Jesús, Tardón Adonina

Abstract excerpt

BACKGROUND AND OBJECTIVE: Alcohol and its metabolites play an important role in carcinogenesis. This effect could be modulated by polymorphisms in genes encoding enzymes involved in the metabolism of alcohol and folate. Therefore, we analyzed the effect of alcohol consumption and ADH1B Arg48His, ADH1B Arg370Cys, ADH1C Ile349Val, ALDH2 Glu540Lys, CYP2E1 RsaI, CYP2E1 DraI, CYP2E1 TaqI and MTHFR C677T polymorphisms...

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Source

Identifiers

PMID: 28236470
DOI: 10.1016/j.medcli.2016.12.033

Genes

ALDH2
MTHFR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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