Article
The role of neuromedin U in adiposity regulation. Haplotype analysis in European children from the IDEFICS Cohort.
PloS one - 1 Jan 2017
Gianfagna Francesco, Grippi Claudio, Ahrens Wolfgang, Bailey Mark E S, Börnhorst Claudia, De Henauw Stefan, Foraita Ronja, Koni Anna C, Krogh Vittorio, Mårild Staffan, Molnár Dénes, Moreno Luis, Pitsiladis Yannis, Russo Paola, Siani Alfonso, Tornaritis Michael, Veidebaum Toomas, Iacoviello Licia
Abstract excerpt
BACKGROUND AND AIMS: Neuromedin U (NMU) is a hypothalamic neuropeptide with important roles in several metabolic processes, recently suggested as potential therapeutic target for obesity. We analysed the associations between NMU gene variants and haplotypes and body mass index (BMI) in a large sample of European children. METHODS AND RESULTS: From a large European multi-center study on childhood obesity, 4,528...
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