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Article

Understanding the links among neuromedin U gene, beta2-adrenoceptor gene and bone health: an observational study in European children.

PloS one - 1 Jan 2013

Gianfagna Francesco, Cugino Daniela, Ahrens Wolfgang, Bailey Mark E S, Bammann Karin, Herrmann Diana, Koni Anna C, Kourides Yiannis, Marild Staffan, Molnár Dénes, Moreno Luis A, Pitsiladis Yannis P, Russo Paola, Siani Alfonso, Sieri Sabina, Sioen Isabelle, Veidebaum Toomas, Iacoviello Licia

Abstract excerpt

Neuromedin U, encoded by the NMU gene, is a hypothalamic neuropeptide that regulates both energy metabolism and bone mass. The beta-2 adrenergic receptor, encoded by the ADRB2 gene, mediates several effects of catecholamine hormones and neurotransmitters in bone. We investigated whether NMU single nucleotide polymorphisms (SNPs) and haplotypes, as well as functional ADRB2 SNPs, are associated with bone stiffness...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 23936460
DOI: 10.1371/journal.pone.0070632
PMCID: PMC3731254

Genes

ADRB2
NMU

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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