Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The association between polymorphisms near TMEM18 and the risk of obesity: a meta-analysis.

BMC medical genomics - 6 Jul 2021

Koj Natalia, Grochowalski Łukasz, Jarczak Justyna, Wójtowicz Weronika, Sobalska-Kwapis Marta, Słomka Marcin, Marciniak Błażej, Strapagiel Dominik

Abstract excerpt

BACKGROUND: Many studies have proposed that the pathogenesis of obesity has a genetic basis, with an important risk factor being the presence of polymorphisms in the region of the TMEM18 gene, which plays a significant role in feeding behaviour; however, subsequent studies among different ethnic populations and age groups have shown inconsistent results. Therefore, this present meta-analysis examines the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Case-Control Studies
Share to Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Membrane Proteins

Share to Obesity

Share to Polymorphism, Single Nucleotide

Share to Risk Factors

Source

Open in PubMed Open full text

Identifiers

PMID: 34229657
DOI: 10.1186/s12920-021-01025-7
PMCID: PMC8259011

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The association between polymorphisms near TMEM18 and the risk of obesity: a meta-analysis.PMID 34229657Read ↗

Drinking Habits and Physical Activity Interact and Attenuate Obesity Predisposition of TMEM18 Polymorphisms Carriers.Semantic proximity Read ↗

The obesity gene, TMEM18, is of ancient origin, found in majority of neuronal cells in all major brain regions and associated with obesity in severely obese children.Semantic proximity Read ↗

Identification of a TMEM182 rs141764639 polymorphism associated with central obesity by regulating tumor necrosis factor-α in a Korean population.Semantic proximity Read ↗

Association of TMEM18 variants with BMI and waist circumference in children and correlation of mRNA expression in the PFC with body weight in rats.Semantic proximity Read ↗

Associations between VMAT1 Polymorphisms and Obesity.Semantic proximity Read ↗

Determination of obesity associated gene variants related to TMEM18 through ultra-deep targeted re-sequencing in a case-control cohort for pediatric obesity.Semantic proximity Read ↗

Association study of common polymorphisms in MSRA, TFAP2B, MC4R, NRXN3, PPARGC1A, TMEM18, SEC16B, HOXB5 and OLFM4 genes with obesity-related traits among Portuguese childrenSemantic proximity Read ↗

Comprehensive evaluation of the neuropeptide-Y gene variants in the risk of obesity: a case-control study and meta-analysis.Semantic proximity Read ↗

Association of obesity susceptibility gene variants with metabolic syndrome and related traits in 1,443 Czech adolescents.Semantic proximity Read ↗

Implication of genetic variants in overweight and obesity susceptibility among the young Arab population of the United Arab Emirates.Semantic proximity Read ↗

The current review of adolescent obesity: the role of genetic factors.Semantic proximity Read ↗

Loss and gain of function experiments implicate TMEM18 as a mediator of the strong association between genetic variants at human Chromosome 2p25.3 and obesitySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.