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Article

Association between polymorphisms of the Nesfatin gene, NUCB2, and obesity in men.

Molecular genetics and metabolism - 1 Jul 2011

Zegers Doreen, Beckers Sigri, Mertens Ilse L, Van Gaal Luc F, Van Hul Wim

Abstract excerpt

Nesfatin-1, which originates from its precursor protein nucleobindin-2 (NUCB2), is a novel appetite-regulating molecule that might be associated with the melanocortin signalling pathway in the hypothalamus. The secreted protein appears to play an important role in metabolic control through its anorexigenic and anti-hyperglycemic effects. Therefore, we hypothesized that polymorphisms in the NUCB2 gene might...

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Source

Identifiers

PMID: 21459029
DOI: 10.1016/j.ymgme.2011.03.007

Genes

NUCB2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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