Article
Prevalence of naturally occurring protease inhibitor resistance-associated variants in hemodialysis and renal transplant patients with hepatitis C virus infection.
European journal of gastroenterology & hepatology - 1 Jul 2017
Tavares Rita C F, Feldner Ana C C A, Pinho João R R, Uehara Silvia N O, Emori Christini T, Carvalho-Filho Roberto J, Silva Ivonete S S, Santana Rúbia A F, de Castro Vanessa F D, Castoli Gregório T F, Cristovão Charliana U, Ferraz Maria L C G
Abstract excerpt
Background NS3 protease inhibitors (PIs) were the first direct antiviral agents used for the treatment of hepatitis C virus. The combination of second-wave PIs with other direct antiviral agents enabled the use of interferon-free regimens for chronic kidney disease patients on dialysis and renal transplant (RTx) recipients, populations in which the use of interferon and ribavirin is limited. However, the...
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