Article
Resistance-associated polymorphisms in Dutch hepatitis C genotype 1a patients with and without HIV infection.
Annals of hepatology - 1 Jan 2000
Lieveld Faydra I, Swaans Niels, Newsum Astrid M, Ho Cynthia K Y, Schinkel Janke, Molenkamp Richard, van der Meer Jan T M, Arends Joop E, Hoepelman Andy I M, Wensing Anne M J, Siersema Peter D, van Erpecum Karel J, Boland Greet J
Abstract excerpt
UNLABELLED: Background and aim. Resistance-associated variants (RAVs) on the NS3 region of the hepatitis C virus (HCV) may be relevant for antiviral therapy, but data in human immunodeficiency virus (HIV) coinfected patients are scarce. We assessed frequencies of NS3 RAVs in patients infected with HCV genotype 1a with or without HIV coinfection. MATERIAL AND METHODS: HCV NS3 amino acids 1-181 were sequenced by...
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