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Placental CpG methylation of infants born extremely preterm predicts cognitive impairment later in life

7 Mar 2018

Abstract excerpt

BACKGROUND: The placenta is the central regulator of maternal and fetal interactions. Perturbations of placental structure and function have been associated with adverse neurodevelopmental outcomes later in life. Placental CpG methylation represents an epigenetic modification with the potential to impact placental function, fetal development and child health later in life. STUDY DESIGN: Genome-wide placental CpG...

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Share to Epigenetics and DNA Methylation
Share to Neonatal and fetal brain pathology
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PMID: 29513726
DOI: 10.1371/journal.pone.0193271

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