Article
Basigin rs8259 Polymorphism Confers Decreased Risk of Chronic Heart Failure in a Chinese Population.
International journal of environmental research and public health - 21 Feb 2017
Li Mu-Peng, Hu Xiao-Lei, Yang Yong-Long, Zhang Yan-Jiao, Zhou Ji-Peng, Peng Li-Ming, Tang Jie, Chen Xiao-Ping
Abstract excerpt
Left ventricular remodeling is an essential risk factor contributing to the pathogenesis of chronic heart failure (CHF). Basigin (BSG) promotes cardiovascular inflammation and myocardial remodeling processes by induction of extracellular matrix metalloproteinases and inflammatory cytokines. BSG rs8259 polymorphism was associated with BSG expression and risk of acute coronary syndrome. Therefore, we investigated...
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