Article
The adenosine deaminase gene polymorphism is associated with chronic heart failure risk in Chinese.
International journal of molecular sciences - 28 Aug 2014
He Hai-Rong, Li Yuan-Jie, He Gong-Hao, Wang Ya-Jun, Zhai Ya-Jing, Xie Jiao, Zhang Wei-Peng, Dong Ya-Lin, Lu Jun
Abstract excerpt
Adenosine (Ado) is an important cardioprotective agent. Since endogenous Ado levels are affected by the enzyme Ado deaminase (ADA), polymorphisms within the ADA gene may exert some effect on chronic heart failure (CHF). This study applied a case-control investigation to 300 northern Chinese Han CHF patients and 400 ethnicity-matched healthy controls in which nine single-nucleotide polymorphisms (SNPs) of ADA were...
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