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Article

Effects of GRK5 and ADRB1 polymorphisms influence on systolic heart failure.

Journal of translational medicine - 1 Feb 2015

Kang Sheng, Hong Xuan, Ruan Chang-wu, Yu Ping, Yu Shan-shan, Chen Ming, Zhang Dai-fu, Fan Hui-min, Liu Zhong-min

Abstract excerpt

BACKGROUND: G-protein receptor kinase 5 (GRK5) Gln41 > Leu and β1-adrenergic receptor (ADRB1) Arg389 > Gly polymorphisms presented the different distribution of genotype frequencies between Caucasian American and African American, and produced the difference in β-blocker treatment effect among th...

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Share to Adrenergic beta-Antagonists
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Molecular Sequence Data

Share to Multivariate Analysis

Share to Polymorphism, Single Nucleotide

Share to Receptors, Adrenergic, beta-1

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Source

Open in PubMed Open full text

Identifiers

PMID: 25638254
DOI: 10.1186/s12967-015-0402-7
PMCID: PMC4345005

Genes

ADRB1
GRK5
SHF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25638254-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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