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CD44 expression in endothelial colony-forming cells regulates neurovascular trophic effect

25 Jan 2017

Abstract excerpt

Vascular abnormalities are a common component of eye diseases that often lead to vision loss. Vaso-obliteration is associated with inherited retinal degenerations, since photoreceptor atrophy lowers local metabolic demands and vascular support to those regions is no longer required. Given the degree of neurovascular crosstalk in the retina, it may be possible to use one cell type to rescue another cell type in...

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PMID: 28138561
DOI: 10.1172/jci.insight.89906

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