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Article

Breast and renal cancer-Derived endothelial colony forming cells share a common gene signature.

European journal of cancer (Oxford, England : 1990) - 1 May 2017

Moccia Francesco, Fotia Vittoria, Tancredi Richard, Della Porta Matteo Giovanni, Rosti Vittorio, Bonetti Elisa, Poletto Valentina, Marchini Sergio, Beltrame Luca, Gallizzi Giulia, Da Prada Gian Antonio, Pedrazzoli Paolo, Riccardi Alberto, Porta Camillo, Zambelli Alberto, D'Incalci Maurizio

Abstract excerpt

BACKGROUND: Neovascularisation supports the metastatic switch in many aggressive solid cancers. Tumour neovessels are mostly lined by endothelial cells sprouting from nearby capillaries, but they could also be contributed by circulating endothelial progenitor cells (EPCs). However, scant information is available about tumour-derived EPCs. METHODS: We carried out the first thorough, unbiased comparison of...

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PMID: 28258798
DOI: 10.1016/j.ejca.2017.01.025

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