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Article

Adult venous endothelium is a niche for highly proliferative and vasculogenic endothelial colony-forming cells.

Journal of vascular surgery - 1 Dec 2017

Green Linden, Ofstein Richard H, Rapp Brian, Saadatzadeh M Reza, Bhavsar Janak R, Fajardo Andres, Dalsing Michael C, Ingram David A, Murphy Michael P

Abstract excerpt

OBJECTIVE: Postnatal resident endothelium of blood vessels has been proposed to represent terminally differentiated tissue that does not replicate. We previously isolated endothelial colony-forming cells (ECFCs) from human umbilical cord blood (CB) and term placenta by using colony-forming assays and immunocytochemistry. We showed that ECFCs are highly proliferative and form functioning vessels in vivo, the...

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Identifiers

PMID: 28655551
DOI: 10.1016/j.jvs.2016.11.059

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