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Article

Hereditary C1 inhibitor deficiency is associated with high spontaneous amidase activity.

Molecular immunology - 1 May 2017

Charignon Delphine, Ghannam Arije, Ponard Denise, Drouet Christian

Abstract excerpt

BACKGROUND: Angioedema diagnosis classically targets the complement system (via C1 inhibitor (C1Inh) function and antigenic C4 level) and contact phase activation (via amidase activity). Bradykinin is responsible for angioedema attacks and is produced from contact phase activation secondary to failed C1Inh control. OBJECTIVE: We aimed to compare the diagnostic performances of spontaneous amidase activity and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 28222330
DOI: 10.1016/j.molimm.2017.01.028

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SERPING1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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