Article
Phenotypic Differences between Asian and African Lineage Zika Viruses in Human Neural Progenitor Cells
27 Jul 2017
Abstract excerpt
The mechanism by which ZIKV causes a range of neurological complications, especially congenital microcephaly, is not well understood. The fact that congenital microcephaly is associated with Asian lineage ZIKV strains raises the question of why this was not discovered earlier. One possible explanation is that Asian and African ZIKV strains differ in their abilities to infect cells of the CNS and to cause...
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