Article
Decreased calcium pump expression in human erythrocytes is connected to a minor haplotype in the ATP2B4 gene.
Cell calcium - 1 Jul 2017
Zámbó Boglárka, Várady György, Padányi Rita, Szabó Edit, Németh Adrienn, Langó Tamás, Enyedi Ágnes, Sarkadi Balázs
Abstract excerpt
Plasma membrane Ca2+-ATPases are key calcium exporter proteins in most tissues, and PMCA4b is the main calcium transporter in the human red blood cells (RBCs). In order to assess the expression level of PMCA4b, we have developed a flow cytometry and specific antibody binding method to quantitatively detect this protein in the erythrocyte membrane. Interestingly, we found several healthy volunteers showing...
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