Article
Mtss1 promotes maturation and maintenance of cerebellar neurons via splice variant-specific effects.
Brain structure & function - 1 Aug 2017
Sistig Thorsten, Lang Fanziska, Wrobel Sebastian, Baader Stephan L, Schilling Karl, Eiberger Britta
Abstract excerpt
Efficient coupling of the actin cytoskeleton to the cell membrane is crucial for histogenesis and maintenance of the nervous system. At this critical interface, BAR (Bin-Amphiphysin-Rvs) proteins regulate membrane bending, shown to be instrumental for mobility and morphogenesis of individual cells. Yet, the systemic significance of these proteins remains largely unexplored. Here, we probe the role of a prominent...
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