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Article

Contribution of p62 to Phenotype Transition of Coronary Arterial Myocytes with Defective Autophagy.

Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology - 1 Jan 2017

Bao Junxiang, Li Guangbi, Yuan Xinxu, Li Pin-Lan, Gulbins Erich

Abstract excerpt

BACKGROUND: Autophagy disorder contributes to dedifferentiation of arterial smooth muscle cells, but the mechanisms are poorly understood. Here, we sought to investigate the role of scaffolding adaptor p62/SQSTM1 (p62) in phenotype switching of mouse coronary arterial myocytes (CAMs) induced by CD38 gene deficiency or lysosomal dysfunction which blocks autophagic flux in the cells. METHODS: Protein expression was...

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Identifiers

PMID: 28214847
DOI: 10.1159/000457877
PMCID: PMC8216328

Genes

CDK1
SQSTM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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