Article
Maternal IGF1 and IGF1R polymorphisms and the risk of spontaneous preterm birth.
Journal of clinical laboratory analysis - 1 Nov 2017
He Jian-Rong, Lai Yu-Mian, Liu Hui-Hui, Liu Guang-Jian, Li Wei-Dong, Fan Xue-Jiao, Wei Xue-Ling, Xia Xiao-Yan, Kuang Ya-Shu, Liu Xiao-Dan, Chen Nian-Nian, Lu Jin-Hua, Chen Qiao-Zhu, Mai Wei-Bi, Xia Hui-Min, Qiu Xiu
Abstract excerpt
BACKGROUND: The insulin-like growth factor (IGF) pathway was involved in the occurrence of spontaneous preterm birth (SPTB), but little is known regarding the relationship between genetic variations in IGF pathway and the risk of SPTB. We aimed to investigate the associations of IGF1 rs972936 and IGF1 receptor (IGF1R) rs2229765 polymorphisms with SPTB risk in a Chinese population. METHOD: A total of 114 cases of...
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