Article
The Association between Maternal/Fetal Insulin Receptor Substrate 1 Gene Polymorphism rs1801278 and Gestational Diabetes Mellitus in a Chinese Population.
Gynecologic and obstetric investigation - 1 Jan 2021
Wu Lingling, Fang Changping, Zhang Jun, Ye Yanchou, Zhao Haiyan
Abstract excerpt
OBJECTIVES: Insulin receptor substrate 1 (IRS1) is a crucial factor in the insulin signaling pathway. IRS1 gene polymorphism rs1801278 in mothers has been reported to be associated with gestational diabetes mellitus (GDM). However, it is not clear whether IRS1 gene polymorphism rs1801278 in fetuses is associated with their mothers' GDM morbidity. The purpose of this study is to analyze the association between...
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