Article
Cluster analysis of spontaneous preterm birth phenotypes identifies potential associations among preterm birth mechanisms.
American journal of obstetrics and gynecology - 1 Sept 2015
Esplin M Sean, Manuck Tracy A, Varner Michael W, Christensen Bryce, Biggio Joseph, Bukowski Radek, Parry Samuel, Zhang Heping, Huang Hao, Andrews William, Saade George, Sadovsky Yoel, Reddy Uma M, Ilekis John
Abstract excerpt
OBJECTIVE: We sought to use an innovative tool that is based on common biologic pathways to identify specific phenotypes among women with spontaneous preterm birth (SPTB) to enhance investigators' ability to identify and to highlight common mechanisms and underlying genetic factors that are responsible for SPTB. STUDY DESIGN: We performed a secondary analysis of a prospective case-control multicenter study of...
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