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Article

β2-Microglobulin participates in development of lung emphysema by inducing lung epithelial cell senescence.

American journal of physiology. Lung cellular and molecular physiology - 1 May 2017

Gao Na, Wang Ying, Zheng Chun-Ming, Gao Yan-Li, Li Hui, Li Yan, Fu Ting-Ting, Xu Li-Li, Wang Wei, Ying Sun, Huang Kewu

Abstract excerpt

β2-Microglobulin (β2M), the light chain of the major histocompatibility complex class I (MHC I), has been identified as a proaging factor and is involved in the pathogenesis of neurodegenerative disorders by driving cognitive and regenerative impairments. However, little attention has focused on the effect of β2M in the development of lung emphysema. Here, we found that concentrations of β2M in plasma were...

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Identifiers

PMID: 28213472
DOI: 10.1152/ajplung.00516.2016
PMCID: PMC5451601

Genes

HFE
TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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