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Article

The -174 G>C Interleukin-6 Gene Polymorphism is Associated with Angiographic Progression of Coronary Artery Disease over a 4-Year Period.

Hellenic journal of cardiology : HJC = Hellenike kardiologike epitheorese - 1 Jan 2000

Toutouzas Konstantinos, Klettas Dimitrios, Anousakis-Vlachochristou Nikolaos, Melidis Konstantinos, Azilazian Zeta, Asimomiti Maria, Karanasos Antonios, Spanos Anastasios, Tsiamis Eleftherios, Nihoyannopoulos Petros, Tousoulis Dimitris

Abstract excerpt

BACKGROUND: Inflammation is a key process underlying the clinical course of coronary artery disease (CAD). C-reactive protein (CRP) and interleukin-6 (IL-6) contribute to its pathophysiology and act as biomarkers. We sought to examine whether known single nucleotide polymorphisms (SNPs) impact CAD progression, reflecting increased inflammation. METHODS: We retrospectively evaluated coronary angiographies of...

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Identifiers

PMID: 28212870
DOI: 10.1016/j.hjc.2017.02.002

Genes

CAD
CRP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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