Changes in allele frequencies of CSF3R and SETBP1 mutations and evidence of clonal evolution in a chronic neutrophilic leukemia patient treated with ruxolitinib

Abstract excerpt

In 2008, the World Health Organization (WHO) recognized the BCR-ABL1 negative myeloproliferative neoplasm (MPN) chronic neutrophilic leukemia (CNL) as a distinct entity based on the features of an increased white blood cell count (WBC) with a preponderance of neutrophils, no increase in blasts, no

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