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Article

Intra-tumor heterogeneity from a cancer stem cell perspective.

Molecular cancer - 16 Feb 2017

Prasetyanti Pramudita R, Medema Jan Paul

Abstract excerpt

Tumor heterogeneity represents an ongoing challenge in the field of cancer therapy. Heterogeneity is evident between cancers from different patients (inter-tumor heterogeneity) and within a single tumor (intra-tumor heterogeneity). The latter includes phenotypic diversity such as cell surface markers, (epi)genetic abnormality, growth rate, apoptosis and other hallmarks of cancer that eventually drive disease...

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Share to Cell Differentiation
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 28209166
DOI: 10.1186/s12943-017-0600-4
PMCID: PMC5314464

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