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Article

Lipidomic approach for stratification of acute myeloid leukemia patients

16 Feb 2017

Abstract excerpt

The pathogenesis and progression of many tumors, including hematologic malignancies is highly dependent on enhanced lipogenesis. De novo fatty-acid synthesis permits accelerated proliferation of tumor cells by providing membrane components but these may also alter physicochemical properties of lipid bilayers, which can impact signaling or even increase drug resistance in cancer cells. Cancer type-specific lipid...

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Share to Acute Myeloid Leukemia Research
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PMID: 28207743
DOI: 10.1371/journal.pone.0168781

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