Article
Correlated mutations select misfolded from properly folded proteins.
Bioinformatics (Oxford, England) - 15 May 2017
Wozniak P P, Vriend G, Kotulska M
Abstract excerpt
MOTIVATION: The recently developed direct coupling analysis (DCA) method has greatly improved the accuracy with which residue-residue contacts can be predicted from multiple sequence alignments. Contact prediction accuracy, though, is still often not sufficient for complete ab initio protein structure prediction. DCA can, however, support protein structure studies in several ways. RESULTS: We show that DCA can...
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