Article
Improving contact predictions by the combination of correlated mutations and other sources of sequence information.
Folding & design - 1 Jan 1997
Olmea O, Valencia A
Abstract excerpt
We have previously developed a method for predicting interresidue contacts using information about correlated mutations in multiple sequence alignments. The predictions generated with this method were clearly better than random but not enough for their use in de novo protein folding experiments....
Topics
- Amino Acid Sequence
- Binding Sites
- Conserved Sequence
- Molecular Structure
- Mutation
- Protein Folding
- Proteins
- Sequence Alignment