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Article

Forecasting residue-residue contact prediction accuracy.

Bioinformatics (Oxford, England) - 1 Nov 2017

Wozniak P P, Konopka B M, Xu J, Vriend G, Kotulska M

Abstract excerpt

MOTIVATION: Apart from meta-predictors, most of today's methods for residue-residue contact prediction are based entirely on Direct Coupling Analysis (DCA) of correlated mutations in multiple sequence alignments (MSAs). These methods are on average ∼40% correct for the 100 strongest predicted contacts in each protein. The end-user who works on a single protein of interest will not know if predictions are either...

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PMID: 29036497
DOI: 10.1093/bioinformatics/btx416
PMCID: PMC5860164

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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