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Autophagy and epithelial–mesenchymal transition: an intricate interplay in cancer

8 Dec 2016

Abstract excerpt

Autophagy and epithelial to mesenchymal transition (EMT) are major biological processes in cancer. Autophagy is a catabolic pathway that aids cancer cells to overcome intracellular or environmental stress, including nutrient deprivation, hypoxia and drugs effect. EMT is a complex transdifferentiation through which cancer cells acquire mesenchymal features, including motility and metastatic potential. Recent...

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PMID: 27929542
DOI: 10.1038/cddis.2016.415

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