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Article

Neuregulin 1 is involved in enteric nervous system development in zebrafish.

Journal of pediatric surgery - 1 Jul 2017

Pu Jiarui, Tang Shaotao, Tong Qiangsong, Wang Guobin, Jia Haibo, Jia Qiong, Li Kang, Li Dan, Yang Dehua, Yang Jun, Li Hang, Li Shuai, Mei Hong

Abstract excerpt

BACKGROUND: Hirschsprung's disease (HD, also known as congenital colon aganglionosis) is a congenital disorder characterized by the absence of intramural ganglion cells in the distal gastrointestinal tract, which results in tonic contraction of the aganglionic gut segment and functional intestinal obstruction. Recent studies have indicated neuregulin 1 (NRG1) as a new candidate gene involved in the development of...

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Source

Identifiers

PMID: 28190554
DOI: 10.1016/j.jpedsurg.2017.01.005

Genes

NRG1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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