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Article

The developmental etiology and pathogenesis of Hirschsprung disease.

Translational research : the journal of laboratory and clinical medicine - 1 Jul 2013

Butler Tjaden Naomi E, Trainor Paul A

Abstract excerpt

The enteric nervous system is the part of the autonomic nervous system that directly controls the gastrointestinal tract. Derived from a multipotent, migratory cell population called the neural crest, a complete enteric nervous system is necessary for proper gut function. Disorders that arise as a consequence of defective neural crest cell development are termed neurocristopathies. One such disorder is...

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Source

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Identifiers

PMID: 23528997
DOI: 10.1016/j.trsl.2013.03.001
PMCID: PMC3691347

Genes

EDNRB
GDNF
NRTN
RET
SHH
SOX10

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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