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Article

PhosphoPICK-SNP: quantifying the effect of amino acid variants on protein phosphorylation.

Bioinformatics (Oxford, England) - 15 Jun 2017

Patrick Ralph, Kobe Bostjan, Lê Cao Kim-Anh, Bodén Mikael

Abstract excerpt

MOTIVATION: Genome-wide association studies are identifying single nucleotide variants (SNVs) linked to various diseases, however the functional effect caused by these variants is often unknown. One potential functional effect, the loss or gain of protein phosphorylation sites, can be induced through variations in key amino acids that disrupt or introduce valid kinase binding patterns. Current methods for...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 28186228
DOI: 10.1093/bioinformatics/btx072

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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