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Article

An Adolescent Substance Prevention Model Blocks the Effect of CHRNA5 Genotype on Smoking During High School.

Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco - 1 Feb 2016

Vandenbergh David J, Schlomer Gabriel L, Cleveland H Harrington, Schink Alisa E, Hair Kerry L, Feinberg Mark E, Neiderhiser Jenae M, Greenberg Mark T, Spoth Richard L, Redmond Cleve

Abstract excerpt

INTRODUCTION: Prevention intervention programs reduce substance use, including smoking, but not all individuals respond. We tested whether response to a substance use prevention/intervention program varies based upon a set of five markers (rs16969968, rs1948, rs578776, rs588765, and rs684513) within the cluster of nicotinic acetylcholine receptor subunit genes (CHRNA5/A3/B4). METHODS: Participants (N = 424) were...

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Source

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Identifiers

PMID: 25941207
DOI: 10.1093/ntr/ntv095
PMCID: PMC4723675

Genes

CHRNA5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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