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Article

The A445C Variant in Apelin Receptor and Diabetic Retinopathy in Tunisian Patients.

Clinical laboratory - 1 Feb 2017

Soualmia Hayet, Midani Fatma, Hadj-Fradj Sondess, Saadi Nedra, Lassoued Mehdi, Messoud Taieb, Gharbi Monia, Ben-Amor Zohra

Abstract excerpt

BACKGROUND: Apelin and apelin receptor (APLN/APLNR) are involved in the retinal neovascularization of diabetic retinopathy (DR). METHODS: This study investigated the impact of the APLNR A445C variant on the risk of DR in a sample of the Tunisian population (100 patients with DR and 105 healthy controls) using PCR-RFLP. RESULTS: The genotype frequencies of the APLNR A445C variant were not significantly different...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 28182349
DOI: 10.7754/Clin.Lab.2016.160424

Genes

APLNR
APLN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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