Article
First description of a D-CE-D hybrid gene on a weak D Type 2 molecular background.
Transfusion - 1 May 2017
Granier Thomas, Chiaroni Jacques, Bailly Pascal, Silvy Monique
Abstract excerpt
BACKGROUND: RhD phenotypes that express a significantly reduced amount of RhD antigen per red blood cell may be mistyped as RhD-negative by standard serologic methods. The molecular identification of weak D Type 1, 2, or 3 carriers allows managing them as RhD-positive and, thus, rationalizes the use of RhD-negative stock units and the administration of Rh-immunoglobulin prophylaxis, avoiding unnecessary costs and...
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