Article
Impact of RHD genotyping on transfusion practice in Denmark and the United States and identification of novel RHD alleles.
Transfusion - 1 Jan 2021
Vege Sunitha, Sprogøe Ulrik, Lomas-Francis Christine, Jakobsen Marianne A, Antonsen Berit, Aeschlimann Judith, Yazer Mark, Westhoff Connie M
Abstract excerpt
BACKGROUND: Reduced D antigen on red blood cells (RBCs) may be due to "partial" D phenotypes associated with loss of epitope(s) and risk for alloimmunization or "weak" D phenotypes that do not lack major epitopes with absence of clinical complications. Genotyping of samples with weak and discrepant D typing is recommended to guide transfusion and RhIG prophylaxis. The goal was to compare the impact of RHD...
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