Article
Single Nucleotide Polymorphism rs10919543 in FCGR2A/FCGR3A Region Confers Susceptibility to Takayasu Arteritis in Chinese Population.
Chinese medical journal - 5 Apr 2016
Qin Fang, Wang Hu, Song Lei, Lu Xi-Li, Yang Li-Rui, Liang Er-Peng, Wang Wei, Zou Yu-Bao, Bian Jin, Wu Hai-Ying, Zhou Xian-Liang, Hui Ru-Tai, Zhang Hui-Min, Jiang Xiong-Jing
Abstract excerpt
BACKGROUND: Takayasu arteritis (TA) is a rare inflammatory arteriopathy of unknown etiology. The aim of this study was to investigate the genetic susceptibility to TA in a Chinese population. METHODS: Four single nucleotide polymorphisms (SNPs) those locate in the IL12B region (rs56167332), the MLX region (rs665268), the FCGR2A/FCGR3A locus (rs10919543), and the HLA-B/MICA locus (rs12524487), associated with TA...
Read the complete abstract on PubMed