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Article

RifZ (AMED_0655) Is a Pathway-Specific Regulator for Rifamycin Biosynthesis in Amycolatopsis mediterranei.

Applied and environmental microbiology - 15 Apr 2017

Li Chen, Liu Xinqiang, Lei Chao, Yan Han, Shao Zhihui, Wang Ying, Zhao Guoping, Wang Jin, Ding Xiaoming

Abstract excerpt

Rifamycin and its derivatives are particularly effective against the pathogenic mycobacteria Mycobacterium tuberculosis and Mycobacterium leprae Although the biosynthetic pathway of rifamycin has been extensively studied in Amycolatopsis mediterranei, little is known about the regulation in rifamycin biosynthesis. Here, an in vivo transposon system was employed to identify genes involved in the regulation of...

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Identifiers

PMID: 28159794
DOI: 10.1128/AEM.03201-16
PMCID: PMC5377510

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Source receipt: pubmed, retrieved 7 Sept 2026.

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