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Genomic epidemiology of rifampicin ADP-ribosyltransferase (Arr) in the Bacteria domain

5 Oct 2021

Abstract excerpt

Arr is an ADP-ribosyltransferase enzyme primarily reported in association with rifamycin resistance, which has been used to treat tuberculosis in addition to Gram-positive infections and, recently, pan-resistant Gram-negative bacteria. The arr gene was initially identified on the Mycolicibacterium smegmatis chromosome and later on Proteobacteria plasmids. This scenario raised concerns on the distribution and...

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Share to Antibiotic Resistance in Bacteria
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PMID: 34611248
DOI: 10.1038/s41598-021-99255-3

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