Article
Treatment of uncomplicated malaria with artesunate plus sulfadoxine-pyrimethamine is failing in Somalia: evidence from therapeutic efficacy studies and Pfdhfr and Pfdhps mutant alleles.
Tropical medicine & international health : TM & IH - 1 Apr 2015
Warsame Marian, Hassan Abdillahi Mohamed, Barrette Amy, Jibril Ali Mohamed, Elmi Husein Haji, Arale Abdulkadir Mohamed, Mohammady Hanan El, Nada Rania A, Amran Jamal Ghilan Hefzullah, Muse Abdikarim, Yusuf Fahmi Essa, Omar Abdiqani Sheikh
Abstract excerpt
OBJECTIVE: Artesunate plus sulfadoxine-pyrimethamine (AS + SP) has been Somalia's national treatment policy since 2006. Routine monitoring of first-line malaria treatment is needed to ensure appropriate national malaria treatment policy and early detection of drug resistance. For this purpose, we conducted therapeutic efficacy studies of AS + SP for the treatment of uncomplicated malaria in Somalia in 2011....
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