Article
Novel FAM134B mutations and their clinicopathological significance in colorectal cancer.
Human genetics - 1 Mar 2017
Islam Farhadul, Gopalan Vinod, Wahab Riajul, Lee Katherine Ting-Wei, Haque Md Hakimul, Mamoori Afraa, Lu Cu-Tai, Smith Robert A, Lam Alfred K-Y
Abstract excerpt
FAM134B is a putative tumour suppressor gene and no mutations in FAM134B have been reported in colorectal cancer (CRC) to date. This study aims to identify FAM134B mutation sites and the clinicopathological significance of the gene in patients with CRC. Eighty-eight colorectal cancers were studied for FAM134B mutations by Sanger sequencing. The mutations in these cancers were then tested for correlations with the...
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