Article
The rs1277306 Variant of the REST Gene Confers Susceptibility to Cognitive Aging in an Elderly Taiwanese Population.
Dementia and geriatric cognitive disorders - 1 Jan 2017
Lin Eugene, Tsai Shih-Jen, Kuo Po-Hsiu, Liu Yu-Li, Yang Albert C, Kao Chung-Feng, Yang Cheng-Hung
Abstract excerpt
BACKGROUND/AIMS: There is growing evidence that the RE1-silencing transcription factor (REST) gene may contribute to cognitive aging and Alzheimer diseases. In this replication study, we reassessed whether single nucleotide polymorphisms (SNPs) within the REST gene are linked with cognitive aging independently and/or through complex interactions in an older Taiwanese population. METHODS: A total of 634 Taiwanese...
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