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Article

Effects of circadian clock genes and environmental factors on cognitive aging in old adults in a Taiwanese population.

Oncotarget - 11 Apr 2017

Lin Eugene, Kuo Po-Hsiu, Liu Yu-Li, Yang Albert C, Kao Chung-Feng, Tsai Shih-Jen

Abstract excerpt

Previous animal studies have indicated associations between circadian clock genes and cognitive impairment . In this study, we assessed whether 11 circadian clockgenes are associated with cognitive aging independently and/or through complex interactions in an old Taiwanese population. We also analyzed the interactions between environmental factors and these genes in influencing cognitive aging. A total of 634...

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Identifiers

PMID: 28412756
DOI: 10.18632/oncotarget.15493
PMCID: PMC5421829

Genes

CLOCK
RORA
RORB
NPAS2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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