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Article

Additive effect of BDNF and REST polymorphisms is associated with improved general cognitive ability.

Genes, brain, and behavior - 1 Oct 2008

Miyajima F, Quinn J P, Horan M, Pickles A, Ollier W E, Pendleton N, Payton A

Abstract excerpt

Brain-derived neurotrophic factor (BDNF) is a pleiotropic protein involved in neuronal proliferation, differentiation, synaptic plasticity and survival. Independent studies investigating association between the functional BDNF Val66Met polymorphism and cognitive abilities have reported some conflicting findings, which may reflect inadequate sample size, variation in testing methods, population stratification or...

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Source

Identifiers

PMID: 18518926
DOI: 10.1111/j.1601-183X.2008.00409.x

Genes

BDNF
REST

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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