Article
Identification of miRNA, lncRNA and mRNA-associated ceRNA networks and potential biomarker for MELAS with mitochondrial DNA A3243G mutation.
Scientific reports - 31 Jan 2017
Wang Wei, Zhuang Qianqian, Ji Kunqian, Wen Bing, Lin Pengfei, Zhao Yuying, Li Wei, Yan Chuanzhu
Abstract excerpt
Researchers in the field of mitochondrial biology are increasingly unveiling of the complex mechanisms between mitochondrial dysfunction and noncoding RNAs (ncRNAs). However, roles of ncRNAs underlying mitochondrial myopathy remain unexplored. The aim of this study was to elucidate the regulating networks of dysregulated ncRNAs in Mitochondrial myopathy, Encephalopathy, Lactic Acidosis, and Stroke-like episodes...
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