Genomic ncRNAs Regulating Mitochondrial Function in Neurodegeneration: A Neglected Clue in the Complex Etiopathogenesis of Multiple Sclerosis

Abstract excerpt

<title>Abstract</title> <p>Multiple sclerosis (MS), the <bold>most prevalent myelinopathy </bold>with unclear etiology, involves mitochondrial dysfunction that critically contributes to oligodendrocyte damage and neurodegeneration. Recent interest has surged around the role of inflammatory ncRNAs in mitochondrial function, particularly in the context of neurodegenerative diseases (NDs) where <bold>neuroinflammati...

Topics

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• Adaptive Immunity
• Autophagy in Disease and Therapy
• Biomarkers
• Disease Susceptibility
• Gene Expression Regulation
• Gene Regulatory Networks
• MicroRNA in disease regulation
• Multiple Sclerosis

Identifiers and source

Literature Corpus work

e9a36e34-9a85-5c9a-adfe-da0cfa2ac650

DOI

10.21203/rs.3.rs-6391900/v1