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Article

[Mitochondrial genome analysis in the probands of six Chinese families with MELAS].

Yi chuan = Hereditas - 1 Nov 2014

Liu Li, Yuquan Shao, Baorong Zhang, Pingping Jiang, Ailian Du, Minxin Guan

Abstract excerpt

Mitochondrial encephalomyopathy, lactic acidosis and stroke-like episodes (MELAS) is a genetically heterogeneous disorder. The most prevalent mitochondrial DNA (mtDNA) mutation associated with MELAS is the m.3243A>G transition in the mitochondrial tRNA(Leu(UUR)) gene. Here, we report the clinical, genetic and molecular characterization of six probands from Han Chinese families with MELAS. Four of six probands...

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Identifiers

PMID: 25567874
DOI: 10.3724/SP.J.1005.2014.1159

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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