Article
SNP variants associated with non-Hodgkin lymphoma (NHL) correlate with human leukocyte antigen (HLA) class II expression.
Scientific reports - 31 Jan 2017
Ten Lik-Chin, Chin Yoon-Ming, Tai Mei-Chee, Chin Edmund Fui-Min, Lim Yat-Yuen, Suthandiram Sujatha, Chang Kian-Meng, Ong Tee-Chuan, Bee Ping-Chong, Mohamed Zahurin, Gan Gin-Gin, Ng Ching-Ching
Abstract excerpt
Large consortia efforts and genome-wide association studies (GWASs) have linked a number of genetic variants within the 6p21 chromosomal region to non-Hodgkin lymphoma (NHL). Complementing these efforts, we genotyped previously reported SNPs in the human leukocyte antigen (HLA) class I (rs6457327) and class II (rs9271100, rs2647012 and rs10484561) regions in a total of 1,145 subjects (567 NHL cases and 578...
Read the complete abstract on PubMed